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WebJul 22, 2016 · TSG-6 from MSCs and recombinant human (rh)TSG-6 all significantly reduced activations of P38 and JNK signaling induced by severe burn and then attenuated excessive inflammations. On the contrary ... WebTSG-6 forms a stable complex with components of the plasma protein inter-alpha-inhibitor (I [alpha]I), a Kunitz-type serine protease inhibitor. TSG-6 and I (alpha)I synergize to inhibit plasmin, a serine protease involved in the activation of matrix metalloproteinases which are part of the proteolytic cascade associated with inflammation. WebTSG. Traditional Speciality Guaranteed. Speciality, Product, Indication. Speciality, Product, Indication. Vote. 1. Vote. TSG. Transcriptional Gene Silencing. cafe warmolts orvelte